- FiteBac® K18 QAMS covalently attaches a well known biocide, AEM 5700 (Dow Corning), to a silane core containing acrylate functionality
- Acrylate functionality allows for co-polymerization within several polymer systems
- Antimicrobial does not migrate from the polymer
- Normal wear of a dental device exposes fresh K18 QAMS offering continuous microbiological protection
- FDA recognized as a New Molecular Entity
- K18 QAMS is FDA cleared for use in the manufacture of 510(k) dental appliances, including dentures and retainers
- Patent protection until 2033
Video Explanation: Example of plaque biofilms containing mixed bacterial-fungal components.
(a) BacLightstained CLSM merged image showing the presence of live (green) fungal hyphae (open arrowhead) within the biovolume of a biofilm taken from a control disk of one subject (subject 21).
(b) The corresponding BacLightstained CLSM merged image showing the presence of dead (red) fungal hyphae killed by the QAMS-containing acrylic (open arrowhead) from an experimental disk of the same subject.
The addition of K18 QAMS to a MMA/PMMA acrylic resin has been shown to improve fracture toughness without adversely affecting flexural modulus and strength of the orthodontic acrylic.
In vitro studies, performed by Dr. Frank Tay, Dental College of Georgia at Augusta University, of orthodontic acrylic resins containing 4–6% K18 QAMS have been shown to possess both in vitro immediate diffusional as well as contact-killing antimicrobial properties when tested with Streptococcus mutans, Actinomyces naeslundii and Candida albicans.